PhD Candidate
CHRISANTHI PINELOPI APOSTOLIDOY
Chrysana@materials.uoc.gr
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Title
Responsive Self-Assembled Peptide Biomaterials and Applications
Supervisor
MITRAKI ANNA, Professor, Materials Science & Technology Dept. - UOC
Committee Members
VELONIA KALLIOPI, Assistant Professor, Materials Science & Technology Dept. - UOC
CHATZINIKOLAIDOU MARIA, Associate Professor, Materials Science & Technology Dept. - UOC
Abstract
My PhD thesis focuses on the design and characterization of self-assembled peptides that will be responsive to external stimuli such as pH, temperature, light etc. In particular, these peptides are capable of forming hydrogels and they can be used as scaffolds for cell attachment and proliferation, or as vehicles for controlled encapsulation and delivery of drugs. Moreover, the designer peptides will be characterized using electron microscopy techniques and Χ-ray fiber diffraction and will be tested for their rheological properties. Subsequently, they will be evaluated for attachment and proliferation of model cell lines and encapsulation and controlled delivery of small molecules. Finally, they will be tested for their potential to be photostructured using femtosecond laser technologies.